01 - Pat shrimp completely dry with paper towels. Season evenly with kosher salt and black pepper.
02 - Set up three shallow bowls. Combine flour, cornstarch, garlic powder, and smoked paprika in the first bowl. Beat eggs in the second bowl. Place panko breadcrumbs in the third bowl.
03 - Dredge each shrimp in the flour mixture, shaking off excess. Dip into beaten eggs, allowing excess to drip off. Press firmly into panko crumbs to coat thoroughly on all sides.
04 - Pour 2 inches of vegetable oil into a deep skillet or Dutch oven. Heat to 350°F over medium-high heat.
05 - Fry shrimp in batches for 2-3 minutes, turning halfway through, until golden brown and crispy. Remove with tongs and drain on paper-towel-lined plate.
06 - In a small saucepan over low heat, melt butter with honey, hot sauce, and red pepper flakes. Whisk until completely combined and heated through, about 2 minutes.
07 - Transfer fried shrimp to a large bowl. Pour hot honey glaze over shrimp and toss until evenly coated. Serve immediately garnished with fresh chives or parsley and lemon wedges.